欢迎访问江苏麦莎实业有限公司网站！
客服热线：18005112962
热搜：试剂盒 标准品
> > R&D Systems
Human/Mouse FoxP3 Antibody
品名：
Human/Mouse FoxP3 Antibody
货号：
RD3210
规格：
 
品牌：
RD
价格：
快速询价

  Product Details

  • Species Reactivity
    Human, Mouse
  • Specificity
    Detects human FoxP3 in direct ELISAs. Detects human and mouse FoxP3 in flow cytometry.
  • Source
    Recombinant Monoclonal Rabbit IgG Clone # 1054C
  • Purification
    Protein A or G purified from cell culture supernatant
  • Immunogen
    E. coli-derived recombinant human FoxP3
    Met1-Leu71
    Accession # Q9BZS1
  • Formulation
    Supplied as a solution in PBS containing BSA, Glycerol and Sodium Azide. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS.
  • Label
    Unconjugated
Preparation and Storage

Human FoxP3 is a 47 kDa member of the P subclass of the FOX (forkhead box) family of transcription factors. It contains a Leu-rich repeat, a C2H2 zinc finger region, and a C-terminal FKH (fork head), DNA-binding domain. Three isoforms for FoxP3 have been reported. All three isoforms share the sequence used as the immunogen. FoxP3 directly associates with NFAT and NFkB, suppressing their activity in CD4+ T cells. In human, FoxP3 is found in CD4+, CD8+ and CD4+CD25+T cells. Over the region used for immunization of the amino acid sequence, mouse FoxP3 is 83% to 88% identical to rat, human, canine, and bovine FoxP3.
  • Long Name:
    Forkhead Box P3
  • Entrez Gene IDs:
    50943 (Human); 20371 (Mouse)
  • Alternate Names:
    AIID; AIIDMGC141961; DIETER; forkhead box P3; Forkhead Box Protein P3; FoxP3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked; IPEX; JM2; MGC141961; MGC141963; PIDX; PIDXMGC141963; SCURFIN; XPID; XPIDpolyendocrinopathy, enteropathy, X-linked

关闭

客户服务热线

18994828059

18005112962

在线客服